Cellular Model Development for Psychiatric Disorders

Introduction of Cellular Model Development for Psychiatric Disorders

In vitro modeling of mental illness is associated with significant economic, social, and personal burdens. Challenges such as disease heterogeneity, incomplete characterization of available drug targets, and limited understanding of complex pathogenesis have impacted the development of new therapies. Recent advances in genetics, molecular biology, and stem cell biology have accelerated our understanding of neuropsychiatric disorders such as autism spectrum disorder (ASD), major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SZ). Cell-based models can better represent and reveal the complexity of the pathophysiology of neuropsychiatric disorders.

Fig. 1 Brain correlates of in vitro iPSC cell phenotypes. (Falk A, et al., 2016)

Cellular Model Development Services for Psychiatric Disorders

The mission of Ace Neuroscience is to provide cellular models from high-quality sources for psychiatric pathology and drug discovery. We strongly believe that the use of effective cellular models increases the clinical relevance of neuroscience research programs. With our cellular models, you can study and model clinically important psychiatric disorders in relevant genetic and cellular environments. Our proven technology platform allows for the mass production of high-quality neurons to meet the greatest project needs.