Developmental and Reproductive Toxicity Evaluation

Developmental and reproductive toxicity evaluation can detect the toxic effects of drugs during the complete reproductive cycle. Our company employs talented and highly trained toxicologists focused on rare disease drug safety evaluation, and can provide you with high-quality developmental and reproductive toxicity evaluation services to help you identify potential risks in subsequent stages of rare disease therapy research and development.

What is Developmental Toxicity?

Developmental toxicity is the study of various developmental abnormalities and their mechanisms caused by exposure to exogenous physical and chemical factors in developing organisms from fertilized egg, pregnancy, and postnatal period until sexual maturity, and provides a basis for risk or safety evaluation of physical and chemical factors and preventive measures. The effects of developmental toxicity on embryonic development include growth retardation, functional defects, malformations, and death.

What is Reproductive Toxicity?

Reproductive toxicity is used to evaluate the effects of drugs on mammalian reproduction. It is closely related to toxicology studies such as acute toxicity, long-term toxicity, and genotoxicity, and is an important link for drugs to enter clinical research and marketing. In the process of drug development, the purpose of reproductive toxicity research is to reflect the effects of drugs on mammalian reproductive function and development through animal experiments and to predict the possible adverse effects on germ cells, conception, pregnancy, delivery, lactation, and other parental reproductive functions, as well as the adverse effects on offspring embryo-fetal development and postnatal development.

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