Fc receptors



Fc receptors (FcRs) are membrane molecules named for their specific binding for the Fc region of the antibody. Majorly distributed on the surface of B lymphocytes, dendritic cells, natural killer cells, neutrophils, etc. FcRs bind to antibodies that are attached to infected cells or invading pathogens and exert protective functions to the immune system through antibody-mediated phagocytosis or antibody-dependent cell-mediated cytotoxicity (ADCC).